Using Yeast Display of Full-length IgG and Bispecific Antibody to Boost the Success of Therapeutic Antibody
Custom Antibody Services
- CDR and SDR grafting.
- Heavy chain CDR3 grafting.
- Chain shuffling and guided selection.
- Binding affinity and specificity.
- Expression level.
- Species cross-reactivity.
- IgG-like bispecific antibody.
- Common light chain isolation.
Benefits of Genekine Technology
- Yeast has quality control machinery similar to mammalian cells.
- Yeast surface display of full-length IgG and bispecific antibodies.
- Natural IgG folding in display.
- Large full-length IgG libraries.
- FACS real-time screening for both high affinity and expression.
- Select antibodies with high affinity, diversity, and developability.
- Isolate common light chains for bispecific antibody.